protein

L1CAM Protein, Mouse (HEK293, His)

HY-P77732

20 μg;50 μg;100 μg

105;200;320 USD

L1CAM Protein, Mouse (HEK293, His)

proteins

HEK293

20 μg;50 μg;100 μg

105;200;320 USD

The L1CAM protein is a neural cell adhesion molecule that plays a key role in cell adhesion dynamics and transmembrane signaling during brain development.It contributes to neuronal migration, axonal growth, fasciculation, and synaptogenesis.L1CAM Protein, Mouse (HEK293, His) is the recombinant mouse-derived L1CAM protein, expressed by HEK293 , with C-His labeled tag.

Mouse

L1CAM protein, a neural cell adhesion molecule, plays a pivotal role in the dynamics of cell adhesion and the generation of transmembrane signals at tyrosine kinase receptors. Its involvement is particularly crucial during brain development, where it contributes to multiple processes, including neuronal migration, axonal growth and fasciculation, and synaptogenesis. In the mature brain, L1CAM continues to exert its influence on the dynamics of neuronal structure and function, participating in synaptic plasticity. Additionally, L1CAM interacts with SHTN1, with the interaction occurring in axonal growth cones. Furthermore, it engages with isoform 2 of BSG, emphasizing its versatility in molecular interactions that impact various aspects of neural development and function.

N-CAM-L1; NCAM-L1; CD171; L1CAM; CAML1; MIC5; CALL; CHL1; CHL-1; FLJ44930; L1CAM-2; MGC132578; HSAS; HSAS1; MASA; S10; SPG1

Greater than 95% as determined by Tris-Bis PAGE.

Lyophilized from 0.22 μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.

Room temperature in continental US; may vary elsewhere.