protein

TMPRSS1/HPN Protein, Human (HEK293, His)

HY-P77693

20 μg;50 μg;100 μg

130;250;400 USD

TMPRSS1/HPN Protein, Human (HEK293, His)

proteins

HEK293

20 μg;50 μg;100 μg

130;250;400 USD

TMPRSS1/HPN is a serine protease that cleaves extracellular substrates and is involved in the proteolytic processing of growth factors such as HGF and MST1/HGFL. In addition to growth factor regulation, TMPRSS1/HPN is also critical for cell growth and morphology maintenance. TMPRSS1/HPN Protein, Human (HEK293, His) is the recombinant human-derived TMPRSS1/HPN protein, expressed by HEK293 , with C-His labeled tag. The total length of TMPRSS1/HPN Protein, Human (HEK293, His) is 373 a.a., with molecular weight of 18-22 kDa&30 kDa.

Human

TMPRSS1/HPN, a serine protease, is involved in the cleavage of various extracellular substrates, contributing to the proteolytic processing of growth factors such as HGF and MST1/HGFL. Beyond its role in growth factor regulation, TMPRSS1/HPN plays a significant part in cell growth and the maintenance of cell morphology. Additionally, this protease is implicated in the proteolytic processing of ACE2, emphasizing its involvement in crucial cellular pathways. Notably, TMPRSS1/HPN mediates the proteolytic cleavage of urinary UMOD, a process essential for the polymerization of UMOD, underscoring its multifunctional role in modulating various biological processes.

Hpxn; FLJ56652; Hemopexin; HPX; HX; Hepsin; HPN; TMPRSS1

Greater than 95% as determined by Tris-Bis PAGE.

Lyophilized from 0.22 μm filtered solution in 20 mM NaAc,150 mM NaCl (pH 5.0). Normally 8% trehalose is added as protectant before lyophilization.

Room temperature in continental US; may vary elsewhere.