protein

GDF-15 Protein, Cynomolgus (Biotinylated, HEK293, Fc)

HY-P77682

20 μg;50 μg;100 μg

405;750;1200 USD

GDF-15 Protein, Cynomolgus (Biotinylated, HEK293, Fc)

Protein

Cynomolgus

20 μg;50 μg;100 μg

405;750;1200 USD

Growth differentiation factor 15 (GDF-15) is a polypeptide hormone belonging to the transforming growth factor β (TGF-β) superfamily. GDF-15 is also known as non-steroidal anti-inflammatory drug activating Gene-1 (NAG-1), placental transforming growth factor-β (PTGFB), prostate-derived factor (PDF), and placental bone morphogenetic protein (PLAB). GDF-15 binds to glial cell-derived neurotrophic factor (GDNF) family receptor alpha-like protein (GFRAL) and is involved in aging, cancer, and metabolic processes. GFRAL-GDF15 does not affect SMAD activity and activates intracellular signals including RET, AKT, ERK1/2, and phospholipase C (PLCγ). GDF-15 Protein, Cynomolgus (Biotinylated, HEK293, Fc) has 112 amino acids expressed by HEK293 cells with N-terminal hFc tag.