GARP&Latent TGF beta Complex Protein, Mouse (HEK293, His) | MedChem Express LLC HY-P77677 product information

product summary

company name :

MedChem Express LLC

product type :

protein

product name :

GARP&Latent TGF beta Complex Protein, Mouse (HEK293, His)

catalog :

HY-P77677

quantity :

20 μg;50 μg;100 μg

price :

237;450;720 USD

more info or order :

MedChem Express LLC product webpage

product information

Catalog Number :

HY-P77677

Product Name :

GARP&Latent TGF beta Complex Protein, Mouse (HEK293, His)

Product Type :

proteins

Host Species :

HEK293

Size :

20 μg;50 μg;100 μg

List Price :

237;450;720 USD

Product Description :

GARP/latent TGF-b1 complexes are potent inducers of Th17 differentiation in the presence of exogenous IL-6 and inducers of Treg in the presence of IL-2. GARP&Latent TGF beta Complex Protein, Mouse (HEK293, His) is a biotinylated recombinant protein (GARP (I18-N628)&TGF-b1 (L30-S390)) produced by HEK293 cells with His tag [1] [2] .

SpeciesSummary :

Mouse

Background :

GARP/latent TGF-b1 complexes are potent inducers of Th17 differentiation in the presence of exogenous IL-6 and inducers of Treg in the presence of IL-2 [1] [2] . GARP/LTGFβ1 complex is expressed at very low levels on freshly explanted Treg, but markedly upregulated following Treg activation in vitro. GARP/Latent TGF-β1 complex on Treg cells modulates the induction of peripherally derived Treg cells during oral tolerance [3]

ALTnames :

LRRC32; GARP; LAP; TGF-beta-1; LRRC32&TGF-beta 1; LRRC32&TGFB1

Purity :

Greater than 95% as determined by Tris-Bis PAGE.

Buffer :

Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4.

Storage :

Room temperature in continental US; may vary elsewhere.

more info or order :

MedChem Express LLC product webpage