protein

CEACAM8/CD66b Protein, Human (285a.a, HEK293, His)

HY-P77629

20 μg;50 μg

125;275 USD

CEACAM8/CD66b Protein, Human (285a.a, HEK293, His)

proteins

HEK293

20 μg;50 μg

125;275 USD

CEACAM8/CD66b protein is a cell surface glycoprotein that promotes calcium-independent heterophil cell adhesion to other carcinoembryonic antigen-related cell adhesion molecules, particularly CEACAM6, in activated neutrophils Especially obvious. CEACAM8/CD66b Protein, Human (285a.a, HEK293, His) is the recombinant human-derived CEACAM8/CD66b protein, expressed by HEK293 , with C-His labeled tag. The total length of CEACAM8/CD66b Protein, Human (285a.a, HEK293, His) is 285 a.a., with molecular weight of 60-70 kDa.

Human

CEACAM8/CD66b protein, a cell surface glycoprotein, actively contributes to cell adhesion in a calcium-independent manner. It primarily mediates heterophilic cell adhesion, forming interactions with other carcinoembryonic antigen-related cell adhesion molecules, including CEACAM6. Notably, the heterophilic interaction with CEACAM8 takes place specifically in activated neutrophils. CEACAM8 operates as a monomer and also forms heterodimers with CEACAM6, engaging in heterodimerization through its Ig-like V-type domain. This emphasizes its role as a versatile cell adhesion molecule, participating in interactions with various partners and highlighting its significance in diverse cellular contexts, particularly in activated neutrophils and during heterophilic adhesion with other CEACAM family members.

CD66b; CEACAM8; CGM6; CD67; NCA-95

Greater than 95% as determined by Tris-Bis PAGE.

Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4. Normally 5% trehalose is added as protectant before lyophilization.

Room temperature in continental US; may vary elsewhere.