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company name :
MedChem Express LLC
product type :
protein
product name :
CD161 Protein, Cynomolgus (HEK293, His)
catalog :
HY-P77592
quantity :
20 μg;50 μg;100 μg
price :
175;315;500 USD
more info or order :
product information
Catalog Number :
HY-P77592
Product Name :
CD161 Protein, Cynomolgus (HEK293, His)
Product Type :
Protein
Host Species :
Cynomolgus
Size :
20 μg;50 μg;100 μg
List Price :
175;315;500 USD
Product Description :
CD161 Protein plays a crucial role in inhibiting NK cell cytotoxicity by activating specific acid sphingomyelinase/SMPD1, elevating ceramide levels. Activation stimulates AKT1/PKB and RPS6KA1/RSK1 kinases, enhancing anti-CD3-induced T-cell proliferation. As a lectin, CD161 binds to Gal-alpha(1,3)Gal and N-acetyllactosamine epitopes, acting as a ligand for CLEC2D/LLT1. Existing as a homodimer, CD161 interacts with acid sphingomyelinase/SMPD1, contributing to its multifaceted immune regulatory functions. CD161 Protein, Cynomolgus (HEK293, His) is the recombinant cynomolgus-derived CD161 protein, expressed by HEK293 , with C-His labeled tag.
more info or order :
company information
MedChem Express LLC
18 Wilkinson Way, Princeton, NJ 08540
sales@medchemexpress.com
http://www.medchemexpress.com609-228-6898
headquarters: USA