protein

Cathepsin L1 Protein, Mouse (HEK293, His)

HY-P7753

5 μg;10 μg;50 μg;100 μg

60;100;280;480 USD

Cathepsin L1 Protein, Mouse (HEK293, His)

proteins

HEK293

5 μg;10 μg;50 μg;100 μg

60;100;280;480 USD

Cathepsin L Protein, Mouse (HEK293, His) is a lysosomal acid cysteine protease, which is associated with tumor occurrence, development, and metastasis.

Mouse

Cathepsin L (CTSL) is a cysteine protease that belongs to the papain-like family (peptidase C1A), which is associated with tumor occurrence, development, and metastasis. Cathepsin L is implicated in invasion and metastasis of tumors, inflammatory status, atherosclerosis, renal disease, diabetes, bone diseases, viral infection and other diseases. Functions of Cathepsin L depend on their subcellular localization: Cathepsin L is involved in cell death and inflammation in the cytoplasm, and it also regulates cell cycle in the nucleus and exert degradative roles in the extracellular environment. Cathepsin L is expressed in all tissues and cell types and the primary function of cysteine cathepsins is proteolysis of protein antigens generated by pathogen endocytosis [1] [2] .

rMuCathepsin L, His; Cathepsin L1; Major excreted protein; p39 cysteine proteinase; CTSL1

Greater than 90% as determined by reducing SDS-PAGE.

Lyophilized from a 0.2 μm filtered solution of 20mM Tris, 150mM NaCl, pH 7.5-8.0. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization.

Room temperature in continental US; may vary elsewhere.