protein

Cadherin-1/CD324 Protein, Human (Biotinylated, HEK293, Fc)

HY-P77518

20 μg

240 USD

Cadherin-1/CD324 Protein, Human (Biotinylated, HEK293, Fc)

proteins

HEK293

20 μg

240 USD

The Cadherin-1/CD324 protein is a calcium-dependent cell adhesion protein that interacts with homology in junctional cells to facilitate cell type sorting. CDH1 is involved in regulating intercellular adhesion, mobility, and epithelial cell proliferation. Cadherin-1/CD324 Protein, Human (Biotinylated, HEK293, Fc) is the recombinant human-derived Cadherin-1/CD324 protein, expressed by HEK293 , with C-hFc labeled tag. The total length of Cadherin-1/CD324 Protein, Human (Biotinylated, HEK293, Fc) is 685 a.a., with molecular weight of ~87.1 KDa.

Human

Cadherin-1 (CD324) is a calcium-dependent cell adhesion protein known for its preference to interact homophilically with itself in adjacent cells, thereby contributing to the sorting of heterogeneous cell types. CDH1, a member of the cadherin family, plays a crucial role in regulating cell-cell adhesions, influencing the mobility and proliferation of epithelial cells. Notably, CDH1 exhibits a potent role as an invasive suppressor and serves as a ligand for integrin alpha-E/beta-7E, impacting non-amyloidogenic degradation of Abeta precursors. Moreover, CDH1 demonstrates a robust inhibitory effect on the production of APP C99 and C83, further emphasizing its multifaceted involvement in cellular processes and its potential implications in pathological contexts.

Cadherin-1; CDH1; CAM 120/80; E-cadherin; CD324

Greater than 90% as determined by reducing SDS-PAGE

Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization.

Room temperature in continental US; may vary elsewhere.