protein

Cathepsin D Protein, Human (HEK293, C-His)

HY-P7748A

5 μg;10 μg;50 μg;100 μg;500 μg

60;100;280;480;1330 USD

Cathepsin D Protein, Human (HEK293, C-His)

proteins

HEK293

5 μg;10 μg;50 μg;100 μg;500 μg

60;100;280;480;1330 USD

Cathepsin D protein is an acidic protease that actively participates in intracellular protein breakdown. Studies have shown that it is critical in the processing of amyloid precursor protein (APP), with ADAM30-mediated cleavage and activation leading to APP degradation. Cathepsin D Protein, Human (HEK293, C-His) is the recombinant human-derived Cathepsin D protein, expressed by HEK293 , with C-6*His labeled tag. The total length of Cathepsin D Protein, Human (HEK293, C-His) is 392 a.a., with molecular weight of ~44.78 kDa.

Human

Cathepsin D, an acid protease, exerts its activity in the intracellular breakdown of proteins. This protease is implicated in the processing of amyloid precursor protein (APP), with its cleavage and activation by ADAM30 leading to the degradation of APP, as evidenced in studies. Cathepsin D's involvement extends to the pathogenesis of various diseases, including breast cancer, and it is suggested to play a role in Alzheimer's disease, highlighting its significance in cellular processes and potential connections to pathological conditions.

rHuCathepsin D, His; Cathepsin D; CTSD; CPSD

Greater than 95% as determined by reducing SDS-PAGE.

Lyophilized from a 0.2 μm filtered solution of 20 mM MES, 150 mM NaCl, pH 5.5.

Room temperature in continental US; may vary elsewhere.