protein

Cathepsin A Protein, Human (HEK293, His, solution)

HY-P7745

10 μg;50 μg

240;704 USD

Cathepsin A Protein, Human (HEK293, His, solution)

proteins

HEK293

10 μg;50 μg

240;704 USD

Cathepsin A Protein, Human (HEK293, His, solution) is a 58-60 kDa human cathepsin A protein with a His-flag. Cathepsin A is a multicatalytic enzyme with carboxypeptidase activities [1] .

Human

Cathepsin A is synthesized as a zymogen, a single-chain precursor of 54 kDa (after signal peptide cleavage and addition of two N-linked glycans) that self-associates into a homodimer. The precursor cathepsin A has two domains, a core domain (1–182 and 303–452) interrupted by a cap domain insertion (183–302). Cathepsin A is a multicatalytic enzyme with deamidase and esterase in addition to carboxypeptidase activities. Cathepsin A, lysosomal carboxypeptidase are components of the lysosomal multienzyme complex along with beta-galactosidase. Cathepsin A activates Neu1 and protects GAL and Neu1 against the rapid proteolytic degradation.

rHuCathepsin A, His; Lysosomal protective protein; CTSA; Carboxypeptidase C; Carboxypeptidase L; Cathepsin A

Greater than 95% as determined by reducing SDS-PAGE.

Supplied as a 0.2 μm filter solution of 20 mM PB, 150 mM NaCl, pH 7.4.

Shipping with dry ice