protein

Langerin/CD207 Protein, Rhesus Macaque (HEK293, Fc)

HY-P77437

2 μg;5 μg;50 μg;100 μg

30;50;200;320 USD

Langerin/CD207 Protein, Rhesus Macaque (HEK293, Fc)

proteins

HEK293

2 μg;5 μg;50 μg;100 μg

30;50;200;320 USD

Langerin, also known as CD207, is a calcium-dependent lectin with mannose-binding specificity. Notably, it induces the formation of Birbeck granules (BG) and acts as an effective regulator of membrane stacking and zipping. Langerin/CD207 Protein, Rhesus Macaque (HEK293, Fc) is the recombinant Rhesus Macaque-derived Langerin/CD207 protein, expressed by HEK293 , with N-hFc labeled tag.

Rhesus Macaque

Langerin, also known as CD207, is a calcium-dependent lectin with a specific affinity for mannose. This protein plays a crucial role in antigen uptake and processing. Langerin induces the formation of Birbeck granules (BGs) and acts as a potent regulator of membrane superimposition and zippering. It demonstrates binding capabilities not only to mannosylated glycans but also to sulfated glycans such as keratan sulfate (KS) and beta-glucans. As a homotrimer, Langerin facilitates the uptake of antigens and is involved in the routing and processing of antigens for presentation to T cells. The multifaceted functions of Langerin highlight its significance in immune response modulation and antigen presentation pathways.

C-type lectin domain family 4 member K; CLEC4K

Greater than 95% as determined by reducing SDS-PAGE.

Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization.

Room temperature in continental US; may vary elsewhere.