protein

IGFBP-5 Protein, Cynomolgus (HEK293, His)

HY-P77394

2 μg;10 μg;50 μg;100 μg;500 μg

55;160;450;765;2100 USD

IGFBP-5 Protein, Cynomolgus (HEK293, His)

proteins

HEK293

2 μg;10 μg;50 μg;100 μg;500 μg

55;160;450;765;2100 USD

IGFBP-5 protein modulates IGFs, extending their life span and regulating their growth effects. It inhibits or stimulates IGFs, showing its dual function. By altering IGFs' interaction with cell receptors, IGFBP-5 fine-tunes growth-associated signaling pathways, governing cellular responses. This interplay reveals IGFBP-5's multifaceted role in cellular growth and proliferation. IGFBP-5 Protein, Cynomolgus (HEK293, His) is the recombinant cynomolgus-derived IGFBP-5 protein, expressed by HEK293 , with C-His labeled tag. The total length of IGFBP-5 Protein, Cynomolgus (HEK293, His) is 252 a.a., with molecular weight of ~35 kDa.

Cynomolgus

IGFBP-5 protein plays a pivotal role in modulating the activity of insulin-like growth factors (IGFs) by extending their half-life. Within cell culture, IGFBP-5 exhibits a dual regulatory function, demonstrating the capacity to either inhibit or stimulate the growth-promoting effects of IGFs. This dynamic influence underscores the intricacy of IGFBP-5's impact on cellular processes. Notably, IGFBP-5 achieves these regulatory effects by modifying the interaction between IGFs and their cell surface receptors, thereby finely regulating the signaling pathways associated with cellular growth and development. The nuanced interplay between IGFBP-5 and IGFs highlights the sophisticated control mechanisms that govern cellular responses to growth factors, shedding light on the multifaceted role of IGFBP-5 in orchestrating cellular growth and proliferation.

Insulin-like growth factor-binding protein 5; IBP-5; IGFBP-5; IBP5

Greater than 95% as determined by reducing SDS-PAGE

Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.

Room temperature in continental US; may vary elsewhere.