protein

Carboxypeptidase E/CPE Protein, Human (HEK293 His)

HY-P7736

10 μg;50 μg

155;430 USD

Carboxypeptidase E/CPE Protein, Human (HEK293 His)

proteins

HEK293

10 μg;50 μg

155;430 USD

Carboxypeptidase E Protein, Human (HEK293 His) is an approximately 57.0 kDa Carboxypeptidase E protein with His-flag, expressed in HEK293-cell system.

Human

Carboxypeptidase E (CPE), which cleaves C-terminal amino acid residues and is involved in neuropeptide processing, is itself subject to intracellular processing Carboxypeptidase E (CPE) is an enkephalin-convertase that cleaved a C-terminal basic residue from enkephalin precursors to generate enkephalin [1] . CPE is a glycoprotein, which is synthesized as a larger inactive precursor. It is exclusively synthesized by membrane-bound polyribosomes in the brain [1] [2] . There exists two forms of CPE, soluble and membrane-bound in most tissues with CPE activity. These two forms differ slightly in molecular weight, but have identical enzymatic properties. Both forms arise from the same precursor, which is encoded by a single gene. This gene is a member of a carboxypeptidase gene family that includes CPA and CPB [2] .

rHuCarboxypeptidase E, His; Carboxypeptidase H; Enkephalin convertase; Prohormone-processing carboxypeptidase

Greater than 95% as determined by reducing SDS-PAGE.

Supplied as a 0.2 μm filter solution of 20 mM Tris-HCl, 150 mM NaCl, 1 mM ZnCl 2 , 10% Glycerol, pH 7.5.

Shipping with dry ice.