protein

Betacellulin/BTC Protein, Cynomolgus (HEK293, Fc)

HY-P77303

2 μg;5 μg;10 μg;50 μg;100 μg

33;60;90;215;340 USD

Betacellulin/BTC Protein, Cynomolgus (HEK293, Fc)

proteins

HEK293

2 μg;5 μg;10 μg;50 μg;100 μg

33;60;90;215;340 USD

Betacellulin/BTC Protein, a member of the epidermal growth factor (EGF) family, is known to play an important role in regulating growth and differentiation of pancreatic beta cells. And it is a growth factor that binds to EGFR, ERBB4 and other EGF receptor family members. In addition, BTC exerts potent mitogenic effects on retinal pigment epithelial cells and vascular smooth muscle cells as a monomer. Betacellulin/BTC Protein, Cynomolgus (HEK293, Fc) is the recombinant cynomolgus-derived Betacellulin/BTC protein, expressed by HEK293 , with C-hFc labeled tag.

Cynomolgus

Betacellulin (BTC), a member of the epidermal growth factor (EGF) family, is known to play an important role in regulating growth and differentiation of pancreatic beta cells. BTC functions as a ligand for the epidermal growth factor receptor (EGFR) and is expressed in a variety of cell types and tissues. And it is a growth factor that binds to EGFR, ERBB4 and other EGF receptor family members. BTC exerts potent mitogenic effects on retinal pigment epithelial cells and vascular smooth muscle cells as a monomer. BTC exerts proliferative activity on beta cells through the activation of ErbB-1 and ErbB-2 receptors, which may increase IRS-2 expression, contributing to the regeneration of beta cells [1] .

Btc; Betacellulin; Betacellulin epidermal growth factor family member

Greater than 95% as determined by reducing SDS-PAGE

Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.

Room temperature in continental US; may vary elsewhere.