protein

UBE2G1 Protein, Human

HY-P77271

5 μg;10 μg;50 μg

45;75;200 USD

UBE2G1 Protein, Human

proteins

E. coli

5 μg;10 μg;50 μg

45;75;200 USD

The UBE2G1 protein is an important participant in the ubiquitin-proteasome system, acting as an E2 ubiquitin-conjugating enzyme to promote the attachment of ubiquitin to different protein substrates. In vitro, UBE2G1 exhibits catalytic ability in “Lys-48” and “Lys-63” linked polyubiquitination reactions. UBE2G1 Protein, Human is the recombinant human-derived UBE2G1 protein, expressed by E. coli , with tag free. The total length of UBE2G1 Protein, Human is 170 a.a., with molecular weight of ~19.5 kDa.

Human

UBE2G1, an essential player in the ubiquitin-proteasome system, serves as an E2 ubiquitin-conjugating enzyme, facilitating the covalent attachment of ubiquitin to diverse protein substrates. In vitro, UBE2G1 showcases its catalytic competence by catalyzing both 'Lys-48'- and 'Lys-63'-linked polyubiquitination reactions. This multifaceted enzyme is implicated in potential roles, including the degradation of muscle-specific proteins, highlighting its involvement in cellular processes related to protein turnover. Additionally, UBE2G1 demonstrates its functional relevance by mediating the polyubiquitination of CYP3A4, a cytochrome P450 enzyme involved in the metabolism of various substrates, underscoring its significance in regulating specific cellular pathways.

Ubiquitin-conjugating enzyme E2 G1; E217K; UBC7; UBE2G1; UBE2G

Greater than 95% as determined by reducing SDS-PAGE

Lyophilized from a 0.2 μm filtered solution of PBS, 10% Glycerol, pH 7.4.

Room temperature in continental US; may vary elsewhere.