protein

TPST1 Protein, Human (HEK293, His)

HY-P77255

5 μg;10 μg;50 μg;100 μg

60;105;290;490 USD

TPST1 Protein, Human (HEK293, His)

proteins

HEK293

5 μg;10 μg;50 μg;100 μg

60;105;290;490 USD

TPST1 (tyrosyl protein sulfotransferase 1) catalyzes the O-sulfation of tyrosine residues located within the acidic motifs of polypeptides, utilizing 3'-phosphoadenylate sulfate (PAPS) as a co-substrate. This enzymatic activity plays a crucial role in post-translational modification processes, especially sulfation, which contributes to the structural and functional diversity of proteins. TPST1 Protein, Human (HEK293, His) is the recombinant human-derived TPST1, expressed by HEK293 , with N-His labeled tag. ,

Human

Tyrosylprotein sulfotransferase 1 (TPST1) is a key enzyme that catalyzes the O-sulfation of tyrosine residues within acidic motifs of polypeptides, utilizing 3'-phosphoadenylyl sulfate (PAPS) as a cosubstrate. This enzymatic process involves the transfer of a sulfate group to tyrosine residues, modulating the structure and function of proteins with acidic motifs. TPST1-mediated tyrosine sulfation is crucial for the post-translational modification of proteins involved in various biological processes, including cell signaling and receptor activation. By participating in the sulfation of tyrosine residues, TPST1 contributes to the diversity of protein modifications, influencing the interactions and activities of sulfated proteins in cellular pathways. This enzyme's role in tyrosine sulfation underscores its importance in the regulation of protein function and cellular signaling events (adapted from the provided passage).

Protein-tyrosine sulfotransferase 1; Tyrosylprotein sulfotransferase 1; TPST-1

Greater than 95% as determined by reducing SDS-PAGE

Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.

Room temperature in continental US; may vary elsewhere.