protein

TMEFF1/Tomoregulin-1 Protein, Mouse (HEK293, Fc)

HY-P77252

5 μg;10 μg;50 μg;100 μg

35;60;165;280 USD

TMEFF1/Tomoregulin-1 Protein, Mouse (HEK293, Fc)

proteins

HEK293

5 μg;10 μg;50 μg;100 μg

35;60;165;280 USD

TMEFF1/Tomoregulin-1 Protein is a transmembrane protein involved in the physiological functions of the central nervous system, embryonic development, and other biological processes. TMEFF1 may inhibit NODAL and BMP signaling during neural patterning. And it may be a tumor suppressor in brain cancers. Additionally, the protein may interact with ST14, implying a molecular association that may contribute to its regulatory and signaling functions. TMEFF1/Tomoregulin-1 Protein, Mouse (HEK293, Fc) is the recombinant mouse-derived TMEFF1/Tomoregulin-1 protein, expressed by HEK293 , with C-hFc labeled tag. The total length of TMEFF1/Tomoregulin-1 Protein, Mouse (HEK293, Fc) is 298 a.a., with molecular weight of ~69 kDa.

Mouse

TMEFF1/Tomoregulin-1 is a transmembrane protein involved in the physiological functions of the central nervous system, embryonic development, and other biological processes. TMEFF1 is expressed in several structures, including alimentary system, brain, ganglia, genitourinary system, and sensory organ. It is implicated in potentially inhibiting NODAL and BMP signaling during neural patterning, suggesting its role in the regulatory processes governing neural development. TMEFF1 is proposed to function as a tumor suppressor in brain cancers, underscoring its potential significance in mitigating abnormal cell growth in neural tissues. Additionally, the protein may interact with ST14, implying a molecular association that may contribute to its regulatory and signaling functions. Furthermore, as an independent prognostic factor for endometrial carcinoma, TMEFF1 promotes the invasion and migration of endometrial carcinoma cells, activates the PI3K/AKT and MAPK signaling pathways, and participates in the regulation of EMT [1] [2] .

TR-1; H7365; Transmembrane protein with EGF-like and one follistatin-like domain; C9orf2

Greater than 95% as determined by reducing SDS-PAGE

Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.

Room temperature in continental US; may vary elsewhere.