protein

THSD1 Protein, Mouse (HEK293, His)

HY-P77231

5 μg;10 μg;50 μg;100 μg

35;60;165;280 USD

THSD1 Protein, Mouse (HEK293, His)

proteins

HEK293

5 μg;10 μg;50 μg;100 μg

35;60;165;280 USD

THSD1 protein actively regulates the assembly of nascent focal adhesions and affects the attachment of endothelial cells to the extracellular matrix. As a key player, THSD1 forms a complex with PTK2/FAK1, TLN1 and VCL and contributes to focal adhesion dynamics. THSD1 Protein, Mouse (HEK293, His) is the recombinant mouse-derived THSD1 protein, expressed by HEK293 , with C-His labeled tag. The total length of THSD1 Protein, Mouse (HEK293, His) is 388 a.a., with molecular weight of ~60-70 kDa.

Mouse

THSD1 emerges as a positive regulator in the assembly of nascent focal adhesions, exerting its influence on the modulation of endothelial cell attachment to the extracellular matrix. As a key participant in this cellular process, THSD1 forms a complex with PTK2/FAK1, TLN1, and VCL, collectively contributing to the intricate orchestration of focal adhesion dynamics. The interaction between THSD1 and TLN1 underscores its involvement in the molecular machinery governing cell-matrix interactions, highlighting its significance in the regulation of focal adhesion formation and endothelial cell adhesion to the extracellular matrix.

Thrombospondin Type-1 Domain-Containing Protein 1; THSD1; TMTSP

Greater than 95% as determined by reducing SDS-PAGE

Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.

Room temperature in continental US; may vary elsewhere.