protein

Stomatin/STOM Protein, Human (HEK293, Fc)

HY-P77216

5 μg;10 μg;50 μg

35;50;145 USD

Stomatin/STOM Protein, Human (HEK293, Fc)

proteins

HEK293

5 μg;10 μg;50 μg

35;50;145 USD

Stomatin/STOM protein is a key regulator of ion channel activity, affecting ASIC2 and ASIC3 to form unique banana-shaped homodimers and higher-order homo-oligomers. It interacts with ASIC1, ASIC2, and ASIC3 to regulate their functions, and forms a complex with LANCL1 to positively regulate SLC4A1 activity. Stomatin/STOM Protein, Human (HEK293, Fc) is the recombinant human-derived Stomatin/STOM protein, expressed by HEK293 , with C-mFc labeled tag. The total length of Stomatin/STOM Protein, Human (HEK293, Fc) is 234 a.a., with molecular weight of ~75 KDa.

Human

Stomatin/STOM protein serves as a key regulator of ion channel activity and transmembrane ion transport. It exerts its influence on ASIC2 and ASIC3 channel activity, forming homodimers and higher-order homooligomers that exhibit a distinctive banana-shaped structure. Stomatin/STOM interacts with ASIC1, ASIC2, and ASIC3, suggesting its involvement in modulating their functions. Additionally, it forms complexes with LANCL1, and its interaction with SLC2A1 positively regulates SLC4A1 activity. Stomatin/STOM is also part of large complexes involving SLC40A1, SLC14A1, SLC29A1, and AQP1, further emphasizing its role in intricate cellular processes. Furthermore, its interaction with STOML1 suggests a potential role in redistributing STOM from the plasma membrane to late endosomes, adding another layer to its regulatory functions.

Erythrocyte band 7 integral membrane protein; Protein 7.2b; BND7; EPB72

Greater than 95% as determined by reducing SDS-PAGE.

Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.

Room temperature in continental US; may vary elsewhere.