protein

SMPDL3A Protein, Mouse (HEK293, His)

HY-P77209

5 μg;10 μg;50 μg;100 μg;500 μg;1 mg

40;70;200;340;950;1615 USD

SMPDL3A Protein, Mouse (HEK293, His)

proteins

HEK293

5 μg;10 μg;50 μg;100 μg;500 μg;1 mg

40;70;200;340;950;1615 USD

SMPDL3A protein hydrolyzes nucleotide triphosphates, particularly ATP, and p-nitrophenyl-TMP. It has limited activity with nucleoside diphosphates and none with nucleoside monophosphates. SMPDL3A also catalyzes the conversion of CDP-choline to CMP and phosphocholine, and CDP-ethanolamine. However, it lacks sphingomyelin phosphodiesterase activity. SMPDL3A Protein, Mouse (HEK293, His) is the recombinant mouse-derived SMPDL3A protein, expressed by HEK293 , with C-His labeled tag. The total length of SMPDL3A Protein, Mouse (HEK293, His) is 423 a.a., with molecular weight of ~49.1 KDa.

Mouse

SMPDL3A protein demonstrates in vitro nucleotide phosphodiesterase activity, specifically with nucleoside triphosphates, including ATP. It also exhibits activity with p-nitrophenyl-TMP, but to a lesser extent with nucleoside diphosphates and lacks activity with nucleoside monophosphates. Additionally, SMPDL3A displays in vitro enzymatic activity with CDP-choline, yielding CMP and phosphocholine, and with CDP-ethanolamine. However, it does not possess sphingomyelin phosphodiesterase activity.

Acid sphingomyelinase-like phosphodiesterase 3a; ASM-like phosphodiesterase 3a; SMPDL3A; ASML3A

Greater than 95% as determined by reducing SDS-PAGE.

Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.

Room temperature in continental US; may vary elsewhere.