protein

Serpin A3C Protein, Mouse (HEK293, His)

HY-P77195

5 μg;10 μg;50 μg

35;60;170 USD

Serpin A3C Protein, Mouse (HEK293, His)

proteins

HEK293

5 μg;10 μg;50 μg

35;60;170 USD

Serpin A3C Protein, with its reactive center loop (RCL), guides interactions with target proteases.Binding leads to protease cleavage at the RCL, forming a stable serpin-protease complex, inactivating the protease.Variability in Serpin A3C's RCL sequences among Serpina3 paralogs may influence the specificity of target protease interactions, showcasing the protein's adaptability.Serpin A3C Protein, Mouse (HEK293, His) is the recombinant mouse-derived Serpin A3C protein, expressed by HEK293 , with C-His labeled tag.

Mouse

Serpin A3C protein features a reactive center loop (RCL) that protrudes from its main body, guiding its interaction with target proteases. Upon binding, the protease cleaves the serpin at the reactive site within the RCL, forming a durable and covalent serpin-protease complex. This complex, marked by the inactivation of the protease, exhibits remarkable stability. The distinct sequences within the RCL of Serpina3 paralogs contribute to the variability, potentially influencing the specificity of target protease interactions.

Serine protease inhibitor A3C; Kallikrein-binding protein; KBP; Klkbp

Greater than 95% as determined by reducing SDS-PAGE

Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.

Room temperature in continental US; may vary elsewhere.