protein

CD162/PSGL-1 Protein, Human (HEK293, His)

HY-P77163

50 μg;100 μg

185;300 USD

CD162/PSGL-1 Protein, Human (HEK293, His)

proteins

HEK293

50 μg;100 μg

185;300 USD

CD162/PSGL-1 Protein, a cell surface receptor, plays a crucial role in leukocyte trafficking and adhesion. Dysregulation of CD162/PSGL-1 Protein has been associated with inflammatory diseases and impaired immune responses. Targeting CD162/PSGL-1 Protein may offer potential therapeutic interventions in these conditions by modulating leukocyte trafficking, enhancing immune responses, and managing inflammatory disorders. CD162/PSGL-1 Protein, Human (HEK293, His) is the recombinant human-derived CD162/PSGL-1 protein, expressed by HEK293 , with C-His labeled tag. The total length of CD162/PSGL-1 Protein, Human (HEK293, His) is 295 a.a., with molecular weight of ~89 & 61 kDa, respectively.

Human

CD162/PSGL-1 Protein is a SLe(x)-type proteoglycan that plays a crucial role in inflammation. It facilitates the rapid rolling of leukocytes over vascular surfaces during the initial stages of inflammation by interacting with E-, P-, and L-selectins through high affinity, calcium-dependent interactions. CD162/PSGL-1 Protein is essential for the initial capture of leukocytes. In addition to its role in inflammation, it also acts as a receptor for enterovirus 71 during microbial infection.

P-selectin glycoprotein ligand 1; PSGL-1; Selectin P ligand; CD162; SELPLG

Greater than 95% as determined by reducing SDS-PAGE

Supplied as a 0.2 μm filtered solution of PBS, pH 7.4.

Shipping with dry ice