protein

Prostasin/PRSS8 Protein, Human (HEK293, His)

HY-P77153

5 μg;10 μg;50 μg

60;100;280 USD

Prostasin/PRSS8 Protein, Human (HEK293, His)

proteins

HEK293

5 μg;10 μg;50 μg

60;100;280 USD

Prostasin/PRSS8, with trypsin-like cleavage specificity, crucially activates the epithelial sodium channel (ENaC) by cleaving its gamma subunits (SCNN1G). This protein forms a heterodimeric complex, consisting of light and heavy chains connected by a disulfide bond. Prostasin/PRSS8 Protein, Human (HEK293, His) is the recombinant human-derived Prostasin/PRSS8 protein, expressed by HEK293 , with C-His labeled tag. The total length of Prostasin/PRSS8 Protein, Human (HEK293, His) is 293 a.a., with molecular weight of ~40 kDa.

Human

Prostasin/PRSS8 protein exhibits trypsin-like cleavage specificity, with a particular affinity for poly-basic substrates. It plays a crucial role in stimulating the activity of the epithelial sodium channel (ENaC) by activating the cleavage of its gamma subunits (SCNN1G). Structurally, it is composed of two chains, a light and a heavy chain, which are held together by a disulfide bond, forming a heterodimeric complex.

Channel-activating protease 1; CAP1; Serine protease 8

Greater than 95% as determined by reducing SDS-PAGE

Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.

Room temperature in continental US; may vary elsewhere.