protein

PILR-beta Protein, Mouse (HEK293, Fc)

HY-P77143

5 μg;10 μg;50 μg;100 μg

35;60;165;280 USD

PILR-beta Protein, Mouse (HEK293, Fc)

proteins

HEK293

5 μg;10 μg;50 μg;100 μg

35;60;165;280 USD

The PILR-β protein is a paired immune system modulator and is considered a signal-activated receptor that associates with cell surface ITAM adapters such as DAP12. It interacts with CD99 and may help natural killer cells recognize target cells and activate dendritic cells. PILR-beta Protein, Mouse (HEK293, Fc) is the recombinant mouse-derived PILR-beta protein, expressed by HEK293 , with C-hFc labeled tag. The total length of PILR-beta Protein, Mouse (HEK293, Fc) is 165 a.a., with molecular weight of 55-60 kDa.

Mouse

PILR-beta Protein, a member of paired receptors integral to immune system regulation, is posited as a cellular signaling activating receptor that forms associations with ITAM-bearing adapter molecules on the cell surface. This protein is suggested to interact with DAP12 and functions as a receptor for CD99, potentially contributing to target cell recognition by natural killer cells and participating in the activation of dendritic cells. The observed interaction with CD99 and the likely association with DAP12 underscore PILR-beta's role in cellular signaling pathways, highlighting its potential impact on immune responses and cellular recognition mechanisms.

Paired immunoglobulin-like type 2 receptor beta; Activating receptor PILR-beta; FDFACT; Pilrb1

Greater than 90% as determined by reducing SDS-PAGE

Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.

Room temperature in continental US; may vary elsewhere.