protein

PBK/TOPK Protein, Human (sf9, His)

HY-P77122

5 μg;10 μg;50 μg;100 μg

80;135;380;650 USD

PBK/TOPK Protein, Human (sf9, His)

Protein

Sf9 insect cells

5 μg;10 μg;50 μg;100 μg

80;135;380;650 USD

PBK/TOPK Protein, a mitosis-specific kinase, phosphorylates MAP kinase p38, emphasizing its specific role in cell division. Implicated in lymphoid cell activation, PBK/TOPK has broader impacts on immune responses. When phosphorylated, it forms a complex with TP53, destabilizing TP53 and dampening the G2/M checkpoint in doxorubicin-induced DNA damage, highlighting its multifaceted functions in cell cycle control and genotoxic stress responses. PBK/TOPK Protein, Human (sf9, His) is the recombinant human-derived PBK/TOPK protein, expressed by Sf9 insect cells , with C-His labeled tag.