protein

OTUB2 Protein, Human (His)

HY-P77118

5 μg;10 μg;50 μg;100 μg;500 μg;1 mg

35;50;90;135;380;600 USD

OTUB2 Protein, Human (His)

proteins

E. coli

5 μg;10 μg;50 μg;100 μg;500 μg;1 mg

35;50;90;135;380;600 USD

OTUB2 is a hydrolase that efficiently removes conjugated ubiquitin from proteins in vitro, implying a crucial role in preventing protein degradation and regulating turnover. Its deubiquitinating activity targets “Lys-11”, “Lys-48” and “Lys-63” linked polyubiquitin chains, with preference for the latter. OTUB2 Protein, Human (His) is the recombinant human-derived OTUB2 protein, expressed by E. coli , with N-6*His labeled tag.

Human

As a hydrolase, OTUB2 exhibits the capacity to efficiently remove conjugated ubiquitin from proteins in vitro, suggesting a pivotal regulatory role in protein turnover by preventing degradation. With its deubiquitination activity, OTUB2 acts on 'Lys-11', 'Lys-48', and 'Lys-63'-linked polyubiquitin chains, displaying a preference for the latter. This specificity underscores OTUB2's selectivity in modulating diverse ubiquitin linkages, emphasizing its potential significance in orchestrating cellular processes related to protein ubiquitination and degradation.

Ubiquitin thioesterase OTUB2; Otubain-2; C14orf137; OTB2; OTU2

Greater than 95% as determined by reducing SDS-PAGE

Lyophilized from a 0.2 μm filtered solution of 50 mM Tris-HCL, 300 mM NaCl, 500 mM arginine, pH 10.0.

Room temperature in continental US; may vary elsewhere.