protein

NGFR Protein, Mouse (HEK293, His)

HY-P77101

2 μg;10 μg;50 μg;100 μg;500 μg

35;60;170;270;800 USD

NGFR Protein, Mouse (HEK293, His)

Protein

HEK293

2 μg;10 μg;50 μg;100 μg;500 μg

35;60;170;270;800 USD

Nerve Growth Factor Receptor (NGFR) also known as CD271, p75NTR, TNFRSF16, is a transmembrane low-affinity receptor for the neurotrophin family. NGFR has no intrinsic tyrosine kinase activity. NGFR can act as a tumour suppressor, negatively regulating cell growth and proliferation. NGF-NGFR cascade activates NF-κB, leading to inhibition of apoptosis, increases survival of schwannoma, and breast cancer cells.  NGFR Protein, Mouse (HEK293, His) is a recombinant protein with a C-Terminal His label, It consists of 243 amino acids (M1-N243) and is produced in HEK293 cells.