protein

MCEMP1 Protein, Human (HEK293, Fc)

HY-P77080

2 μg;5 μg;10 μg;50 μg;100 μg

30;60;90;200;300 USD

MCEMP1 Protein, Human (HEK293, Fc)

proteins

HEK293

2 μg;5 μg;10 μg;50 μg;100 μg

30;60;90;200;300 USD

MCEMP1, a lung-specific surface protein, is a type II transmembran protein. MCEMP1 is primarily expressed in myeloid lineage immune cells and plays a critical in allergic and inflammatory lung diseases. MCEMP1 is an adaptor for KIT receptor to promotes stem cell factor-mediated mast cell proliferation. MCEMP1 also participates in the chemotaxis, adhesion, and migration of circulating monocytes [1] [2] . MCEMP1 Protein, Human (HEK293, Fc) is the recombinant human-derived MCEMP1 protein, expressed by HEK293 , with N-mFc labeled tag. The total length of MCEMP1 Protein, Human (HEK293, Fc) is 81 a.a., with molecular weight of 40-50 kDa.

Human

MCEMP1, a lung-specific surface protein, is a type II transmembran protein. MCEMP1 is primarily expressed in myeloid lineage immune cells, such as lung-resident mast cells and alveolar macrophages. MCEMP1 is an inducible genes in many inflammatory diseases, and plays a critical in allergic and inflammatory lung diseases [1] . In function, MCEMP1 is an adaptor for KIT receptor to promotes stem cell factor-mediated mast cell proliferation. MCEMP1 signals through its cytoplasmic immunoreceptor tyrosine-based activation motif and forms a complex with KIT to enhance its autophosphorylation and activation [1] . MCEMP1 also participates in the chemotaxis, adhesion, and migration of circulating monocytes [2] .Human MCEMP1 shares about 40% aa sequence identity with mouse and rat. Rat MCEMP1 shares about 78% aa sequence identity with mouse.

Mast cell-expressed membrane protein 1; C19orf59

Greater than 95% as determined by reducing SDS-PAGE

Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4.

Room temperature in continental US; may vary elsewhere.