protein

LPAL2 Protein, Human (HEK293, Fc)

HY-P77066

5 μg;10 μg;50 μg;100 μg

40;70;200;340 USD

LPAL2 Protein, Human (HEK293, Fc)

proteins

HEK293

5 μg;10 μg;50 μg;100 μg

40;70;200;340 USD

LPAL2 is a pseudogene and modulates tumor growth, metastasis and stemness phenotypes of HCC. LPAL2 is a biomarker in malignant cholangiocytes. LPAL2/miR-1287-5p axis modulates TGF-β1–induced increases in cell adhesion factor levels and thyroid eye disease (TED) orbital fibroblast activation through EGFR/AKT signaling. LPAL2 Protein, Human (HEK293, Fc) is the recombinant human-derived LPAL2 protein, expressed by HEK293 , with C-mFc labeled tag.

Human

LPAL2 is a Pseudogene. LPAL2 Protein modulates tumor growth, metastasis and stemness phenotypes of HCC cell lines by modulating MMP9 expression. LPAL2 is a tumor-suppressor lncRNA in HCC [1] . Besides, LPAL2 is also associated with thyroid eye disease. Specifically, LPAL2/miR-1287-5p axis modulates TGF-β1–induced increases in cell adhesion factor levels and thyroid eye disease (TED) orbital fibroblast activation through EGFR/AKT signaling. In TED orbital tissues, expression of the lncRNA LPAL2 is upregulated and positively correlated with ICAM-1 and ICAM-4 expression. LPAL2 directly targets miR-1287-5p to inhibit its expression [2] . LPAL2 is also a biomarker in malignant cholangiocytes [3] .

Putative apolipoprotein(a)-like protein 2; Apo(a)-like protein 2; APOARGC

Greater than 95% as determined by reducing SDS-PAGE

Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization.

Room temperature in continental US; may vary elsewhere.