protein

LDLRAD3 Protein, Human (HEK293, Fc)

HY-P77057

5 μg;10 μg;50 μg

40;70;200 USD

LDLRAD3 Protein, Human (HEK293, Fc)

proteins

HEK293

5 μg;10 μg;50 μg

40;70;200 USD

LDLRAD3 protein significantly affects the processing of amyloid precursor protein (APP), possibly reducing soluble APP-α (sAPP-α) and increasing the production of amyloid P3 peptide. Suggested regulation of ITCH and NEDD4 E3 ligases. LDLRAD3 Protein, Human (HEK293, Fc) is the recombinant human-derived LDLRAD3 protein, expressed by HEK293 , with C-hFc labeled tag.

Human

The LDLRAD3 protein appears to have a significant impact on amyloid precursor protein (APP) processing, potentially leading to decreased production of soluble APP-alpha (sAPP-alpha) and an increase in the generation of the amyloidogenic P3 peptide. Furthermore, it is suggested to play a regulatory role in the activity and degradation of ITCH and NEDD4 E3 ligases, as indicated by studies. In the context of microbial infection, LDLRAD3 acts as a receptor for the Venezuelan equine encephalitis virus. These findings underscore the multifunctional nature of LDLRAD3, implicating it in key cellular processes related to protein processing, immune response, and viral interactions.

Low-density lipoprotein receptor class A domain-containing protein 3; LRAD3

Greater than 90% as determined by reducing SDS-PAGE

Supplied as a 0.2 μm filtered solution of PBS, pH 7.4.

Shipping with dry ice