protein

IL-36RN Protein, Mouse

HY-P77007

2 μg;10 μg;50 μg;100 μg;500 μg;1 mg

36;100;280;476;1330;2200 USD

IL-36RN Protein, Mouse

proteins

E. coli

2 μg;10 μg;50 μg;100 μg;500 μg;1 mg

36;100;280;476;1330;2200 USD

IL-36RN protein exhibits cytokine activity, interleukin 1 receptor antagonist activity, and interleukin 1 receptor binding activity. It negatively regulates IL-6 production and is predicted to be localized in the cytoplasm and extracellular regions. IL-36RN Protein, Mouse is the recombinant mouse-derived IL-36RN protein, expressed by E. coli , with tag free. The total length of IL-36RN Protein, Mouse is 154 a.a., with molecular weight of ~17 kDa.

Mouse

IL-36RN protein is predicted to possess several important functional attributes, including cytokine activity, interleukin-1 receptor antagonist activity, and interleukin-1 receptor binding activity. It plays a role upstream of or within the negative regulation of interleukin-6 production. The protein is predicted to be located in both the cytoplasm and extracellular region, suggesting its potential involvement in diverse cellular processes. Furthermore, IL-36RN is anticipated to be active in the extracellular space. In humans, this gene is associated with pustular psoriasis 14, indicating its relevance in skin pathology. Notably, IL-36RN shares orthology with the human interleukin 36 receptor antagonist (IL36RN). Expression analysis reveals biased expression in the adult stomach (RPKM 9.0) and lung (RPKM 1.0), underscoring its potential significance in these tissues.

IL-36RA; Interleukin-36 Receptor Antagonist Protein; IL-1RP3; IL-1F5; IL-1L1; FIL1D; IL1HY1

Greater than 90% as determined by reducing SDS-PAGE

Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4 or 20 mM PB, 150 mM NaCl, pH 7.4.

Room temperature in continental US; may vary elsewhere.