protein

CD316/IGSF8 Protein, Mouse (HEK293, His)

HY-P76985

2 μg;5 μg;10 μg;50 μg;100 μg

35;60;95;235;350 USD

CD316/IGSF8 Protein, Mouse (HEK293, His)

proteins

HEK293

2 μg;5 μg;10 μg;50 μg;100 μg

35;60;95;235;350 USD

The CD316/IGSF8 protein plays a key role in functions related to CD81 and CD9, affecting oocyte fertilization and may affect HCV function. It regulates keratinocyte proliferation, acts as a negative regulator of cell motility, and binds to CD82 to inhibit prostate cancer cell migration. CD316/IGSF8 Protein, Mouse (HEK293, His) is the recombinant mouse-derived CD316/IGSF8 protein, expressed by HEK293 , with C-His labeled tag.

Mouse

The CD316/IGSF8 protein appears to play a pivotal role in a variety of functions attributed to CD81 and CD9, such as oocyte fertilization and potential involvement in hepatitis C virus function. Additionally, it is implicated in regulating the proliferation and differentiation of keratinocytes and may act as a negative regulator of cell motility, suppressing T-cell mobility in coordination with CD81, associating with CD82 to suppress prostate cancer cell migration, and regulating epidermoid cell reaggregation and motility on laminin-5 with CD9 and CD81 as crucial linkers. CD316/IGSF8 might also contribute to integrin-dependent morphology and motility functions, participating in the regulation of neurite outgrowth and the maintenance of the neural network in the adult brain. Interactions with CD82, CD9/tetraspanin-29, integrin alpha-3/beta-1, and integrin alpha-4/beta-1 are suggested, with additional participation in a complex composed of CD9, PTGFRN, and CD81. Furthermore, direct interaction with CD81/tetraspanin-28 is noted, emphasizing the intricate network of associations that define the diverse roles of CD316/IGSF8 in cellular processes.

Immunoglobulin superfamily member 8; EWI-2; KCT-4; LIR-D1; PGRL; CD316; IGSF8

Greater than 95% as determined by reducing SDS-PAGE.

Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.

Room temperature in continental US; may vary elsewhere.