protein

Butyrylcholinesterase/BCHE Protein, Human (HEK293, His)

HY-P7690

10 μg;50 μg

165;496 USD

Butyrylcholinesterase/BCHE Protein, Human (HEK293, His)

proteins

HEK293

10 μg;50 μg

165;496 USD

Butyrylcholinesterase/BCHE Protein, Human (HEK293, His) is a recombinant human butyrylcholinesterase (BuChE) produced in HEK293 cells, with His tag. BuChE, one of cholinesterases, is a serine hydrolase closely related to acetylcholinesterase [1] .

Human

Butyrylcholinesterase is a serine hydrolase closely related to acetylcholinesterase (AChE). Both enzymes have similar three-dimensional-structure. Though their catalytic mechanisms are similar, they display different substrate specificity and inhibitor sensitivity. BuChE is present in plasma and numerous vertebrate tissues. Unlike AChE that plays a key role in terminating the action of acetylcholine in cholinergic system, no direct involvement of BuChE in cholinergic system has been demonstrated. However, BuChE may be a surrogate for AChE in case of deficiency of this enzyme [1] .

rHuBCHE, His; Butyrylcholine Esterase; BCHE; Choline Esterase II

Greater than 95% as determined by reducing SDS-PAGE.

Supplied as a 0.2 μm filter solution of 20 mM TrisHCl, 150 mM NaCl, pH 7.5.

Shipping with dry ice.