protein

DNAJC30 Protein, Human (His)

HY-P76873

5 μg;10 μg;50 μg;100 μg

40;70;200;340 USD

DNAJC30 Protein, Human (His)

proteins

E. coli

5 μg;10 μg;50 μg;100 μg

40;70;200;340 USD

DNAJC30 is a neuron-enriched mitochondrial protein that plays a critical regulatory role in mitochondrial respiration. It binds to the ATP synthase complex and promotes ATP synthesis. DNAJC30 Protein, Human (His) is the recombinant human-derived DNAJC30 protein, expressed by E. coli , with N-His labeled tag. The total length of DNAJC30 Protein, Human (His) is 86 a.a., with molecular weight of ~14 kDa.

Human

DNAJC30, a mitochondrial protein enriched in neurons, assumes a crucial role as a regulator of mitochondrial respiration. This protein associates with the ATP synthase complex, playing a facilitative role in ATP synthesis. Additionally, it acts as a potential chaperone involved in the turnover of the subunits of mitochondrial complex I N-module, contributing to the degradation of N-module subunits damaged by oxidative stress and thereby enhancing the functional efficiency of complex I. Notably, DNAJC30's interaction with MT-ATP6 and ATP5MC2, both direct, underscores its involvement in these mitochondrial processes, shedding light on its significance in maintaining mitochondrial function and cellular homeostasis.

DnaJ homolog subfamily C member 30; WBSCR18

Greater than 95% as determined by reducing SDS-PAGE

Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.

Room temperature in continental US; may vary elsewhere.