protein

CYB5R1 Protein, Human (His)

HY-P76856

5 μg;10 μg;50 μg

45;75;200 USD

CYB5R1 Protein, Human (His)

proteins

E. coli

5 μg;10 μg;50 μg

45;75;200 USD

CYB5R1 is an important member of the NADH-cytochrome b5 reductase family and plays a crucial role in fatty acid desaturation, cholesterol biosynthesis, drug metabolism, and erythrocyte methemoglobin reduction. Utilizing NADH, CYB5R1 promotes the reduction of cytochrome b5, contributing to enzymatic processes in lipid metabolism, sterol synthesis, and drug biotransformation. CYB5R1 Protein, Human (His) is the recombinant human-derived CYB5R1 protein, expressed by E. coli , with N-His labeled tag. The total length of CYB5R1 Protein, Human (His) is 277 a.a., with molecular weight of ~33.5 kDa.

Human

CYB5R1, a member of the NADH-cytochrome b5 reductase family, plays a crucial role in diverse biological processes such as fatty acid desaturation and elongation, cholesterol biosynthesis, drug metabolism, and methemoglobin reduction in erythrocytes. As an essential component of these metabolic pathways, CYB5R1 utilizes NADH as a cofactor to facilitate the reduction of cytochrome b5, contributing to the enzymatic processes involved in lipid metabolism, sterol synthesis, and drug biotransformation. In erythrocytes, CYB5R1's involvement in methemoglobin reduction underscores its significance in maintaining hemoglobin functionality and preventing oxidative stress. The multifunctional nature of CYB5R1 positions it as a key player in cellular processes crucial for lipid homeostasis, hemoglobin function, and drug metabolism.

NADH-cytochrome b5 reductase 1; b5R.1; Humb5R2; NQO3A2

Greater than 95% as determined by reducing SDS-PAGE

Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.

Room temperature in continental US; may vary elsewhere.