protein

CNTN5/Contactin-5 Protein, Human (HEK293, His)

HY-P76841

5 μg;10 μg;50 μg

50;85;240 USD

CNTN5/Contactin-5 Protein, Human (HEK293, His)

proteins

HEK293

5 μg;10 μg;50 μg

50;85;240 USD

CNTN5/Contactin-5 protein mediates cell surface interactions in nervous system development, promoting neurite outgrowth in cerebral cortical neurons but not in hippocampal neurons. It is involved in auditory system neuronal activity and interacts with PTPRG, potentially regulating neuronal functions and connectivity. CNTN5/Contactin-5 Protein, Human (HEK293, His) is the recombinant human-derived CNTN5/Contactin-5 protein, expressed by HEK293 , with C-His labeled tag. The total length of CNTN5/Contactin-5 Protein, Human (HEK293, His) is 1041 a.a., with molecular weight of ~115-150 kDa.

Human

Contactin-5 (CNTN5) plays a crucial role in mediating cell surface interactions during nervous system development. While it exhibits neurite outgrowth-promoting activity in cerebral cortical neurons, it does not exert the same effect in hippocampal neurons. CNTN5 is implicated in neuronal activity within the auditory system, highlighting its potential role in sensory processes. Furthermore, it interacts with protein tyrosine phosphatase receptor gamma (PTPRG), suggesting a molecular partnership that may contribute to the regulation of neuronal functions and connectivity.

Contactin-5; Neural recognition molecule NB-2; hNB-2

Greater than 95% as determined by reducing SDS-PAGE

Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.

Room temperature in continental US; may vary elsewhere.