protein

CNDP2 Protein, Human (sf9, His)

HY-P76837

10 μg

320 USD

CNDP2 Protein, Human (sf9, His)

proteins

Sf9 insect cells

10 μg

320 USD

The CNDP2 protein is a catalyst that coordinates the oxidative cleavage of heme at the α-methylene bridge carbon, releasing carbon monoxide (CO) and generating biliverdin IXalpha. This enzymatic process releases ferrous iron from the central heme iron chelate. CNDP2 Protein, Human (sf9, His) is the recombinant human-derived CNDP2 protein, expressed by Sf9 insect cells , with C-His labeled tag.

Human

HO-2/HMOX2 protein serves as a catalyst in the oxidative cleavage of heme at the alpha-methene bridge carbon, liberating carbon monoxide (CO) and producing biliverdin IXalpha. This enzymatic process results in the release of the central heme iron chelate as ferrous iron. HO-2/HMOX2 plays a crucial role in the breakdown of heme, facilitating the controlled generation of signaling molecules such as CO and biliverdin. The release of CO, in particular, has various physiological implications, contributing to vascular homeostasis, anti-inflammatory responses, and cellular protection. This enzyme's activity is integral to the regulation of heme metabolism and the maintenance of cellular redox balance.

Cytosolic non-specific dipeptidase; CNDP dipeptidase 2; Peptidase A; CN2; CPGL; HEL-S-13; PEPA

Greater than 90% as determined by reducing SDS-PAGE

Supplied as a 0.2 μm filtered solution of 50 mM Tris, 100 mM NaCl, 0.5 mM PMSF, pH 8.0.

Shipping with dry ice