protein

CEP57 Protein, Human (His)

HY-P76818

5 μg;10 μg;50 μg;100 μg

40;70;200;340 USD

CEP57 Protein, Human (His)

proteins

E. coli

5 μg;10 μg;50 μg;100 μg

40;70;200;340 USD

CEP57 is a centrosomal protein that is a potential player in promoting microtubule attachment to centrosomes, possibly by forming a ring-like structure around microtubules. The protein exhibits homodimer and homooligomer formation and interacts with microtubules. CEP57 Protein, Human (GST) is the recombinant human-derived CEP57 protein, expressed by E. coli , with N-GST labeled tag. The total length of CEP57 Protein, Human (GST) is 109 a.a., with molecular weight of 35-43 kDa.

Human

CEP57 (Centrosomal Protein 57) is a centrosomal protein with a potential role in microtubule attachment to centrosomes, possibly by forming ring-like structures around microtubules. Its involvement extends to mediating the nuclear translocation and mitogenic activity of the internalized growth factor FGF2, distinguishing its interaction from that of FGF1. CEP57 exists as a homodimer and homooligomer, and it interacts with microtubules, as well as with FGF2 and RAP80. Notably, it does not exhibit interaction with FGF1 or the 24 kDa isoform of FGF2. These features suggest that CEP57 plays a multifaceted role in cellular processes, including microtubule dynamics and the regulation of growth factor-mediated signaling pathways. It has to outline CEP57's potential functions in microtubule attachment, interaction with growth factors, and its oligomeric nature.

Centrosomal protein of 57 kDa; Cep57; Translokin; KIAA0092; TSP57

Greater than 95% as determined by reducing SDS-PAGE

Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.

Room temperature in continental US; may vary elsewhere.