protein

CD204/MSR1 Protein, Rat (HEK293, His)

HY-P76784

5 μg;10 μg;50 μg;100 μg

40;65;180;290 USD

CD204/MSR1 Protein, Rat (HEK293, His)

proteins

HEK293

5 μg;10 μg;50 μg;100 μg

40;65;180;290 USD

CD204/MSR1 Protein is a homo-trimeric transmembrane glycoprotein, holds key inflammatory roles in multiple pathophysiologic processes. MSR1 is highly expressed in lung, arteries, and adipose tissue [1] . CD204/MSR1 Protein, Rat (HEK293, His) is the recombinant rat-derived CD204/MSR1 protein, expressed by HEK293 , with N-His labeled tag.

Rat

MSR1, also known as scavenger receptor-A (SR-A) or cluster of differentiation 204 (CD204), holds key inflammatory roles in multiple pathophysiologic processes. Present primarily on the surface of various types of macrophage, this receptor variably affects processes such as atherosclerosis, innate and adaptive immunity, lung and liver disease, and more recently, cancer. MSR1 has been shown to be important for M2 polarisation. Therefore, the role it carries or MSR1 is in part determined by the type of macrophage in which MSR1 is expressed and location within which the macrophages reside. The role of MSR1 is often dichotomous, being either host protective or detrimental to the pathogenesis of disease [1] .

Macrophage scavenger receptor types I and II; SCARA1

Greater than 95% as determined by reducing SDS-PAGE

Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.

Room temperature in continental US; may vary elsewhere.