protein

PVR/CD155 Protein, Rat (HEK293, His)

HY-P76774

5 μg;10 μg;50 μg;100 μg;500 μg;1 mg

40;70;200;340;1080;1835 USD

PVR/CD155 Protein, Rat (HEK293, His)

proteins

HEK293

5 μg;10 μg;50 μg;100 μg;500 μg;1 mg

40;70;200;340;1080;1835 USD

The PVR/CD155 protein, encoded by the PVR gene, acts as a receptor for poliovirus. It is involved in the regulation of heterophilic and homophilic cell adhesion, as well as leukocyte-mediated cytotoxicity. PVR/CD155 Protein, Rat (HEK293, His) is the recombinant rat-derived PVR/CD155 protein, expressed by HEK293 , with C-His labeled tag. The total length of PVR/CD155 Protein, Rat (HEK293, His) is 319 a.a., with molecular weight of ~54 -75 kDa.

Rat

The PVR gene encodes the poliovirus receptor (PVR), also known as CD155, which functions as a virus receptor. PVR is predicted to be involved in heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules, homophilic cell adhesion via plasma membrane adhesion molecules, and positive regulation of leukocyte-mediated cytotoxicity. It is anticipated to act upstream of or within processes such as cell migration and cell-cell adhesion, and is predicted to be located in the cell surface and plasma membrane, serving as an integral component of the membrane with activity in adherens junctions. The orthologous counterpart in humans is PVR (PVR cell adhesion molecule). With biased expression observed in the lung (RPKM 65.2), heart (RPKM 42.8), and nine other tissues, PVR/CD155 plays a vital role in mediating cell adhesion and potentially influencing immune responses.

Poliovirus receptor; Nectin-like protein 5; NECL-5; CD155; PVR; PVS

Greater than 95% as determined by reducing SDS-PAGE

Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.

Room temperature in continental US; may vary elsewhere.