protein

BAI3 Protein, Human (HEK293, His)

HY-P7675

5 μg;10 μg;50 μg;100 μg;500 μg;1 mg

60;100;250;400;1200;1750 USD

BAI3 Protein, Human (HEK293, His)

proteins

HEK293

5 μg;10 μg;50 μg;100 μg;500 μg;1 mg

60;100;250;400;1200;1750 USD

BAI3 Protein, Human (HEK293, His) is a recombinant human brain-specific angiogenesis inhibitor 3 produced in HEK293 cells. Brain-specific angiogenesis inhibitor 3 (BAI3) is a member of the cell-adhesion class of G protein-coupled receptors that are expressed at high levels in the brain. BAI3 is a high-affinity receptor for C1q-like proteins [1] .

Human

BAI3 is from the adhesion group of seven-transmembranespanning G protein-coupled receptors (GPCRs) and has been identified via gene expression profiling asbeing upregulated in small-cell lung cancer (SCLC) tumors. It has subsequently been validated as a sen-sitive and specific immunohistochemical marker for SCLC, helping to differentiate these tumors frommorphologically similar large-cell neuroendocrine (LCNEC) malignancies [2] .

rHuBAI3, His; Brain-Specific Angiogenesis Inhibitor 3; BAI3

Greater than 95% as determined by reducing SDS-PAGE.

Lyophilized after extensive dialysis against 20 mM PB, 150 mM NaCl, 5% Thehalose, pH 7.2-7.4 or PBS, pH 7.4, 8% trehalose.

Room temperature in continental US; may vary elsewhere.