protein

VTI1A Protein, Human (HEK293, His)

HY-P76700

5 μg;10 μg;50 μg;100 μg;500 μg;1 mg

40;70;200;340;950;1615 USD

VTI1A Protein, Human (HEK293, His)

proteins

HEK293

5 μg;10 μg;50 μg;100 μg;500 μg;1 mg

40;70;200;340;950;1615 USD

VTI1A protein is a V-SNARE that mediates vesicle trafficking and promotes lipid bilayer fusion by interacting with t-SNARE on target membranes. It plays a role in vesicle trafficking from late endosomes to the trans-Golgi network. VTI1A Protein, Human (HEK293, His) is the recombinant human-derived VTI1A protein, expressed by HEK293 , with N-His labeled tag. The total length of VTI1A Protein, Human (HEK293, His) is 187 a.a., with molecular weight of ~29 & 25 & 20 kDa, respectively.

Human

VTI1A, a vesicle-associated soluble N-ethylmaleimide-sensitive factor attachment protein receptor (V-SNARE), plays a crucial role in mediating vesicle transport pathways through interactions with target membrane t-SNAREs, contributing to the specificity of vesicle trafficking and facilitating lipid bilayer fusion. This protein is implicated in vesicular transport from late endosomes to the trans-Golgi network and participates, along with VAMP7, in a non-conventional RAB1-dependent traffic route to the cell surface used by KCNIP1 and KCND2. Additionally, VTI1A may be associated with increased cytokine secretion observed during cellular senescence. It interacts with distinct SNARE complexes containing either STX5 or STX6, and forms a complex with NAPA and, to a lesser extent, with NAPG. Furthermore, VTI1A is identified in a complex alongside STX6, STX12, VAMP4, and itself, highlighting its role in diverse intracellular trafficking processes.

Vesicle transport through interaction with t-SNAREs homolog 1A; Vti1-rp2

Greater than 95% as determined by reducing SDS-PAGE

Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.

Room temperature in continental US; may vary elsewhere.