protein

S100A14 Protein, Human (His)

HY-P76584

5 μg;10 μg;50 μg;100 μg

75;125;350;595 USD

S100A14 Protein, Human (His)

proteins

E. coli

5 μg;10 μg;50 μg;100 μg

75;125;350;595 USD

S100A14 Protein modulates P53/TP53 levels, influencing cell survival and apoptosis. It can either promote cell proliferation or apoptosis and regulates cell migration by modulating MMP2 levels, a P53/TP53-controlled matrix protease. S100A14 does not bind calcium. S100A14 Protein, Human (His) is the recombinant human-derived S100A14 protein, expressed by E. coli , with N-His labeled tag. The total length of S100A14 Protein, Human (His) is 103 a.a., with molecular weight of ~13 kDa.

Human

S100A14 protein exerts a regulatory influence on cellular processes by modulating P53/TP53 protein levels, thereby contributing to the intricate balance between cell survival and apoptosis. Its functional impact is context-dependent, playing a role in either promoting cell proliferation or apoptosis. Additionally, S100A14 is implicated in the regulation of cell migration through its modulation of MMP2 levels, a matrix protease regulated by P53/TP53 transcriptional control. Notably, S100A14 functions independently of calcium binding and forms homodimers, while also interacting with AGER. This intricate interplay highlights the multifaceted role of S100A14 in cellular dynamics and underscores its potential significance in various physiological contexts.

Protein S100-A14; S100 calcium-binding protein A14; S114; S100A14; S100A15

Greater than 85% as determined by reducing SDS-PAGE

Lyophilized from a 0.2 μm filtered solution of 50 mM Tris, 20% Glycerol, pH 7.5. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization.

Room temperature in continental US; may vary elsewhere.