protein

PRMT3 Protein, Human (His)

HY-P76551

5 μg;10 μg

40;65 USD

PRMT3 Protein, Human (His)

proteins

E. coli

5 μg;10 μg

40;65 USD

PRMT3 protein is a multifunctional protein arginine N-methyltransferase. As a type I methyltransferase, it catalyzes monomethylation and asymmetric dimethylation of arginine residues in target proteins. In addition to its methyltransferase role, PRMT3 may also regulate retinoic acid synthesis and signaling by inhibiting ALDH1A1 retinal dehydrogenase activity. PRMT3 Protein, Human (His) is the recombinant human-derived PRMT3 protein, expressed by E. coli , with N-10*His labeled tag. The total length of PRMT3 Protein, Human (His) is 530 a.a., with molecular weight of ~65 kDa.

Human

PRMT3 protein, a versatile protein-arginine N-methyltransferase, catalyzes the monomethylation and asymmetric dimethylation of the guanidino nitrogens of arginine residues in target proteins, categorizing it as a type I methyltransferase. In addition to its role as a methyltransferase, PRMT3 is implicated in potentially regulating retinoic acid synthesis and signaling by inhibiting ALDH1A1 retinal dehydrogenase activity, highlighting its involvement in modulating key cellular processes. The dual enzymatic activities of PRMT3 underscore its significance in the post-translational modification of proteins and suggest its potential impact on diverse biological pathways, particularly those related to retinoic acid metabolism and signaling.

Protein arginine N-methyltransferase 3; PRMT3; HRMT1L3

Greater than 95% as determined by reducing SDS-PAGE.

Lyophilized from a 0.2 μm filtered solution of 50 mM Tris-HCL, 300 mM NaCl, pH 7.4.

Room temperature in continental US; may vary elsewhere.