protein

Bcl-2-like protein 2 Protein, Human (His)

HY-P7653

5 μg;10 μg;50 μg;100 μg;500 μg

35;60;165;280;785 USD

Bcl-2-like protein 2 Protein, Human (His)

proteins

E. coli

5 μg;10 μg;50 μg;100 μg;500 μg

35;60;165;280;785 USD

Bcl-2-like protein 2 is a key regulator that promotes cell survival and prevents dexamethasone-induced apoptosis, which is critical for postmitotic Sertoli cells. It inhibits BAX, emphasizing its role in survival mechanisms. Bcl-2-like protein 2 Protein, Human (His) is the recombinant human-derived Bcl-2-like protein 2 protein, expressed by E. coli , with C-6*His labeled tag. The total length of Bcl-2-like protein 2 Protein, Human (His) is 171 a.a., with molecular weight of ~18.0 kDa.

Human

Bcl-2-like protein 2, a crucial player in cellular dynamics, exerts its influence by promoting cell survival and effectively blocking dexamethasone-induced apoptosis. This multifunctional protein plays a pivotal role in the survival of postmitotic Sertoli cells, where it suppresses the death-promoting activity of BAX. The intricate molecular network extends to interactions with HIF3A through its C-terminus domain, emphasizing its involvement in complex signaling pathways. Additionally, Bcl-2-like protein 2 engages in interactions with BOP, further highlighting its role in cellular homeostasis. The nuanced functions of Bcl-2-like protein 2 underscore its significance in orchestrating cell survival mechanisms and warrant further exploration to comprehensively understand its molecular contributions in diverse cellular contexts.

rHuBcl-2-like protein 2, His; Bcl-2-Like Protein 2; Apoptosis Regulator Bcl-W; BCL2L2; KIAA0271

Greater than 95% as determined by reducing SDS-PAGE.

Supplied as a 0.2 μm filter solution of 25 mM HEPES, 100 mM KCl, 20% Glycerol, pH 7.5 or 20 mM HEPES, 150 mM NaCl, pH 7.4.

Shipping with dry ice