BIRC5 Protein, Human | MedChem Express LLC HY-P7645 product information

product summary

company name :

MedChem Express LLC

product type :

protein

product name :

BIRC5 Protein, Human

catalog :

HY-P7645

quantity :

10 μg;50 μg

price :

105;314 USD

more info or order :

MedChem Express LLC product webpage

product information

Catalog Number :

HY-P7645

Product Name :

BIRC5 Protein, Human

Product Type :

proteins

Host Species :

E. coli

Size :

10 μg;50 μg

List Price :

105;314 USD

Product Description :

BIRC5 Protein, Human, a protein in the intrinsic apoptotic pathway that interacts with XIAP and DIABLO leading to caspase-3 and caspase-9 inactivation. BIRC5 (survivin) is also involved in stabilizing the microtubule-kinetochore dynamics [1] .

SpeciesSummary :

Human

Background :

BIRC5 expression is strongly upregulated in neuroblastoma compared with normal tissues, adult malignancies, and non-malignant fetal adrenal neuroblasts [1] . IRC5/Survivin enhances aerobic glycolysis and drug resistance by altered regulation of the mitochondrial fusion/fission machinery [2] .

ALTnames :

rHuBIRC5; Baculoviral IAP Repeat-Containing Protein 5; Apoptosis Inhibitor 4; BIRC5; Survivin; BIRC5

Purity :

Greater than 95% as determined by reducing SDS-PAGE.

Buffer :

Lyophilized after extensive dialysis against 20 mM Tris, 0.1M NaCl, pH 7.5.

Storage :

Room temperature in continental US; may vary elsewhere.

more info or order :

MedChem Express LLC product webpage