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company name :
MedChem Express LLC
product type :
protein
product name :
IL-18R beta/IL-1R7 Protein, Human (HEK293, Fc)
catalog :
HY-P76425
quantity :
5 μg;10 μg;50 μg;100 μg
price :
49;84;235;400 USD
more info or order :
product information
Catalog Number :
HY-P76425
Product Name :
IL-18R beta/IL-1R7 Protein, Human (HEK293, Fc)
Product Type :
Protein
Host Species :
HEK293
Size :
5 μg;10 μg;50 μg;100 μg
List Price :
49;84;235;400 USD
Product Description :
IL-18 is a pleiotropic proinflammatory cytokine that is involved in induction of inflammatory mediators, regulation of the cytotoxic activity of NK cells and T cells, and differentiation and activation of both Th1 and Th2 cells. IL-18 signals through its specific cell surface receptor IL-18R, which comprises two subunits: IL-18Rα and IL-18R beta. IL-18 forms a signalling complex with the IL-18 receptor α (Rα) and β (Rβ) chains at the plasma membrane, which induces multiple inflammatory cytokines. IL-18R complex recruits the IL-1R- activating kinase and TNF- associated factor 6, which phosphorylates nuclear factor kβ- inducing kinase, with subsequent activation of NF- kβ.IL-18R betaknockdown inhibits IL-18 driven tumor cell metastasis in C57/BL6 mice.IL-18R beta/IL-1R7 Protein, Human (HEK293, Fc) is a recombinant protein with a Fc label that is produced by HEK293 cells.
more info or order :
company information
MedChem Express LLC
18 Wilkinson Way, Princeton, NJ 08540
sales@medchemexpress.com
http://www.medchemexpress.com609-228-6898
headquarters: USA