protein

GGT5 Protein, Human (HEK293, His)

HY-P76361

5 μg;10 μg;50 μg;100 μg

60;105;290;490 USD

GGT5 Protein, Human (HEK293, His)

proteins

HEK293

5 μg;10 μg;50 μg;100 μg

60;105;290;490 USD

The GGT5 protein is an important glycosaminoglycan lyase that selectively cleaves heparin and heparan sulfate using a β-elimination mechanism. It targets specific linkages, such as alpha-D-GlcNp2S6S(1->4) alpha-L-IdoAp2S in heparin and alpha-D-GlcNp2Ac(or 2S)6OH(1->4)beta- in heparan sulfate D-GlcAp. GGT5 Protein, Human (HEK293, His) is the recombinant human-derived GGT5 protein, expressed by HEK293 , with N-His labeled tag. The total length of GGT5 Protein, Human (HEK293, His) is 557 a.a., with molecular weight of ~23-27 & 48-61.8 KDa.

Human

Heparinase II is a glycosaminoglycan-cleaving protein that utilizes a beta-elimination mechanism to cleave both heparin and heparan sulfate. Specifically, it targets heparin at the alpha-D-GlcNp2S6S(1->4) alpha-L-IdoAp2S linkage and heparan sulfate at the alpha-D-GlcNp2Ac(or 2S)6OH(1->4)beta-D-GlcAp linkage. This enzymatic activity contributes to the regulation of glycosaminoglycan composition and function, impacting cellular processes influenced by these molecules. The precise cleavage sites underscore the specificity of Heparinase II in modifying the structure of heparin and heparan sulfate, implicating its role in diverse physiological and pathological contexts where these glycosaminoglycans are involved.

Glutathione hydrolase 5 proenzyme; GGT-rel; GGT 5; GGTLA1

Greater than 95% as determined by reducing SDS-PAGE

Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.

Room temperature in continental US; may vary elsewhere.