protein

FSTL5 Protein, Human (HEK293, His)

HY-P76351

5 μg;10 μg;50 μg;100 μg;500 μg

40;70;200;340;950 USD

FSTL5 Protein, Human (HEK293, His)

proteins

HEK293

5 μg;10 μg;50 μg;100 μg;500 μg

40;70;200;340;950 USD

FSTL5 is an extracellular matrix-secreted protein. FSTL5 promotes cell proliferation and survival by influencing the Wnt/β-catenin signaling pathway in liver cancer and inhibits the progression of liver cancer by inducing Caspase-dependent apoptosis and regulating Bcl-2 family proteins. FSTL5 Protein, Human (HEK293, His) is the recombinant human-derived FSTL5 protein, expressed by HEK293 , with C-His labeled tag.

Human

FSTL5 is an extracellular matrix-secreted protein with a molecular structure similar to follicular listatin (FST). Follistatin-like (FSTL) family proteins are involved in cell migration, proliferation, differentiation and organ development. FST can bind to transforming growth factor β (TGF-β) family activating proteins to promote hepatocyte apoptosis and inhibit hepatocyte proliferation. FST can directly bind to TGF-β3 and inhibit EMT in mammary epithelial cells. Down-regulation of FSTL5 promotes cell proliferation and survival by influencing Wnt/β-catenin signaling pathway in liver cancer and inhibits liver cancer progression by inducing Caspase-dependent apoptosis and regulating Bcl-2 family proteins [1] [2] [3] .

Follistatin-related protein 5; Follistatin-like protein 5; KIAA1263

Greater than 95% as determined by reducing SDS-PAGE

Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.

Room temperature in continental US; may vary elsewhere.