protein

Fas/CD95 Protein, Cynomolgus (HEK293)

HY-P76330

2 μg;10 μg;50 μg;100 μg

33;80;190;290 USD

Fas/CD95 Protein, Cynomolgus (HEK293)

Protein

HEK293

2 μg;10 μg;50 μg;100 μg

33;80;190;290 USD

Fas receptor is a cell surface death receptor, can bind to Fas ligand to form death-inducing signaling complexes, such as Fas associated death domain proteins (FADD). Fas receptor participates in the caspase cascade and regulate the activation of JNK and p38-K downstream. It is also involved in the signaling cascade of ERK/JNK MAPKs, activating MAPK3/ERK1, MAPK8/JNK and NF-κB, which has been implicated in the pathogenesis of various malignant tumors and immune system diseases. Macaca mulatta Fas receptor contain a death domain (228-312 a.a.) that plays a key role in regulating programmed death. Fas/CD95 Protein, Cynomolgus (HEK293) has a full length of 173 amino acids (M1-D173), produced in HEK293 cells with tag free.